What is nrbc in blood test?

NRBC stands for Nucleated Red Blood Cells. A normal blood test should show zero NRBCs. Their presence indicates a serious medical condition.

Here's what you need to know:

• What they are: Mature red blood cells (RBCs) in adults lack a nucleus. NRBCs are immature red blood cells that do have a nucleus. Their presence in the peripheral blood (the blood circulating throughout the body) is abnormal. In the bone marrow, where blood cells are produced, they are expected.

• Why they appear in blood tests: The bone marrow releases NRBCs into the bloodstream when there's a significant need for more red blood cells. This usually signals a problem, such as:

  • Severe anemia: Conditions like hemolytic anemia (where red blood cells are destroyed prematurely) or aplastic anemia (where the bone marrow doesn't produce enough blood cells) can trigger the release of NRBCs.
  • Acute blood loss: Significant blood loss can cause the bone marrow to rush immature cells into circulation.
  • Bone marrow disorders: Conditions affecting the bone marrow, such as leukemia or myelofibrosis, can lead to the release of NRBCs.
  • High altitude: At high altitudes, the body may compensate for lower oxygen levels by releasing NRBCs. This is generally a temporary and less serious condition compared to the others.

• What a positive result means: A positive NRBC result on a blood test requires further investigation. The doctor will likely order additional tests to determine the underlying cause. The number of NRBCs detected (reported as the number of NRBCs per 100 WBCs, for instance) can give clues as to the severity of the problem.

• It's not a standalone diagnosis: The presence of NRBCs doesn't diagnose a specific condition on its own. It's a sign that something is wrong and warrants further medical evaluation.

In short: Finding NRBCs in a blood test is a serious finding that requires prompt medical attention to identify and treat the underlying cause. Do not attempt self-diagnosis or treatment. Discuss the results with your doctor.